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Etikettepilepsi-fruktsamhet-graviditet
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[broderbob]
4/25/18, 11:50 AM

Pregnant women, epilepsy, topiramate

Dec. 27 in the journal Neurology.

Pregnant women with epilepsy who take the drug topiramate during their first trimester may boost the risk that their child will be born with a cleft lip or cleft palate.

Researchers found that pregnant women with epilepsy who take the drug topiramate during their first trimester may boost the risk that their child will be born with a cleft lip or cleft palate.

That risk increase specifically applies to women with epilepsy, who typically take topiramate at an average daily dosage of 200 milligrams.

Hela artikeln finns att läsa

https://www.upi.com/Widely-used-epilepsy-drug-may-raise-risk-for-birth-defects/5621514408947/

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[broderbob]
4/25/18, 2:21 PM
#1

January 23, 2018

High Doses of Topiramate for Epilepsy in Pregnancy Increase Risks for Oral Offspring

Data suggest that the use of topiramate in the first trimester of pregnancy increases the risk for oral clefts in offspring, particularly infants born to women with epilepsy because of higher drug doses, according to the results of a population-based cohort study published in Neurology.

https://www.neurologyadvisor.com/epilepsy/epilepsy-treatment-topiramate-during-pregnancy-risk-oral-clefts/article/738632/

[broderbob]
4/25/18, 2:33 PM
#2

02.01.2018

Topiramate in early pregnancy can increase risk of oral clefts in babies

Using topiramate - an anti-epileptic drug - in early pregnancy, particularly at high doses, could increase the risk of oral clefts in babies.

This is according to new research by the US’ Brigham and Women's Hospital (BWH) and the Harvard TH Chan School of Public Health.

The International Federation of Gynecology and Obstetrics (FIGO)

Hela artikeln finns att läsa nedan

https://www.figo.org/news/topiramate-early-pregnancy-can-increase-risk-oral-clefts-babies-0015800

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